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CHAPTER 5 Cells: The Little Chambers
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The separated 46 chromosomes are thus moved into opposite poles or ends of the cell Finally, a cleavage furrow appears as a narrow groove between the two pinching-o poles of the parent cell The cleavage furrow is eventually replaced on either side by a complete new cell membrane The ultimate result two separate daughter cells, each with an identical set of 46 single chromosomes of their own Eventually, each of these daughter cells enters into its own Cell Cycle, beginning with another interphase By this means, body growth and replacement of worn or damaged cells readily occurs within our human body tissues
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Cancer: A Severe Disorder of Mitosis
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In a normal mitosis, the orderly duplication and division of chromosomes, along with the division of the cytoplasm, creates two identical daughter cells Both of these daughter cells are normal, as well Thus, they go about doing whatever body task they have been genetically programmed to perform Epithelial cells, for example, frequently divide and replace themselves with daughters, each daughter cell in turn performing a body covering or cavitylining function But what can happen if an abnormal change (mut) or mutation (mewTAY-shun) in the genetic program occurs One of the really bad results can be cancer! The English meaning (and the astrological sign) for cancer, of course, is the crab ! An alternate translation for cancer is creeping ulcer Cancer is like a stubborn crab that can a ict either epithelial tissues (like the skin) or connective tissues (such as bone) When a person has a cancer, it is like a crab with pinchers, because it seems to hold on and not let go, making it very di cult to treat! Even worse, cancer has the characteristics of a creeping ulcer, because it often spreads from one a ected site of the body, to many other sites Small wonder, then, that various forms of cancer are a leading cause of death in many countries around the world The exact cause of cancer in human beings, unfortunately, is still unknown But various chemical agents, called carcinogens (car-SIN-ohjens), are suspected cancer or crab (carcin) producers (-gens) Prominent among these suspected carcinogens are the poisonous or toxic chemicals present in cigarette smoke, which are thought to be the leading cause of lung cancer The carcinogens may trigger abnormal changes (mutations) in the DNA of epithelial or connective tissue cells The mutations create errors in the genetic program of the Cell Cycle, such that the resulting daughter cells are highly abnormal The mutated, cancerous daughter cells
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PART 2 Universal Building Blocks of Life
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have a largely unregulated, disorganized, and extremely rapid rate of mitosis When these cancerous cells form larger tumors, the tumors interfere with the function and nutrition of normal cells Eventually, the normal tissue cells die or are crowded out If this process goes on long enough, the cell metabolism of the a ected person may be so abnormally changed that the person dies
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Quiz
Refer to the text in this chapter if necessary A good score is at least 8 correct answers out of these 10 questions The answers are found in the back of this book 1 The word, cell, comes from the Latin for: (a) Crabs (b) Mice (c) Little people (d) A chamber The Modern Cell Theory: (a) Explains that the cell is the basic unit of all living things (b) Holds that, while cells are important, one must seek better explanations of anatomy and physiology at a di erent level of biological organization (c) Was not supported by drawings of tissues viewed through a microscope (d) Supports the concept that cell abnormality has no relationship to disease An organelle always lacking from a prokaryote cell (such as a bacterium): (a) Ribosome (b) ER (c) Mitochondrion (d) Nucleus Organelles that store digestive enzymes: (a) Lysosomes (b) Mitochondria (c) Nuclear membranes (d) Microtubules
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