vb.net qr code generator THE PROCESS OF MUSCLE FIBER EXCITATION in .NET framework

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THE PROCESS OF MUSCLE FIBER EXCITATION
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The released neurotransmitter molecules di use across the narrow, saltwater lled gap of the neuromuscular junction, then attach to transmitter binding sites on the muscle ber What happens to the muscle ber, then, is largely determined by the nature of the neurotransmitter molecules that are released and attached to the binding sites Excitatory neurotransmitter molecules stimulate or excite the skeletal muscle ber to contract The main excitatory neurotransmitter in the human neuromuscular junction is called acetylcholine (uh-see-tul-KOH-leen), abbreviated as ACh
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Motor Pathways
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The neuromuscular junction (motor end plate) can be considered the functional end of a particular motor pathway A motor pathway is a sequence of one or more motor neurons that carries an action potential to a neuromuscular junction, thereby resulting in muscle contraction From this de nition, you can see that a lower motor neuron is the one whose axon and axon terminals actually makes a neuromuscular junction with one or more skeletal muscle bers Where is the cell body of this lower motor neuron located the inquiring mind needs to know Quite often, the cell body of the lower motor neuron is located in the gray matter of the spinal cord (Figure 149) The axon then extends outward into the white matter, entering a spinal nerve The spinal nerve travels some distance away from the spinal cord The motor neuron axons within the spinal nerve carry the action potential away from the central region of the whole body, and hence to the outer portion or periphery (per-IF-eh-ree) As it reaches the body periphery, the spinal nerve branches into one or more peripheral (per-IF-er-al) nerves It is the
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PART 4 Anatomy and Physiology of Animals
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peripheral nerve, then, that forms the last major linkage in the motor pathway From here, the axon terminals of the lower motor neuron branch out and make a neuromuscular junction with one or more skeletal muscle bers Excitatory neurotransmitter (such as acetylcholine, ACh) is released, the skeletal muscle bers are stimulated, and the bers contract The spinal nerves and individual peripheral nerves leading to various skeletal muscles are considered parts of the Peripheral Nervous System or PNS This name is due to the fact that they supply the body periphery (outer portion)
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Gray matter White matter Lower motor neuron Action potential SPINAL CORD (cut in cross-section)
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Fig 149
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Skeletal muscle fibers contract
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Axon
Spinal nerve
Peripheral nerve
A lower motor neuron and its pathway
HIGHER MOTOR NEURONS WITHIN THE CNS
We have explained how a lower motor neuron in the gray matter of the spinal cord can excite skeletal muscle bers to contract The next question to consider is, What is it that excites a lower motor neuron, so that it can then excite skeletal muscle The answer is that a series of one or more higher motor neurons within a particular motor pathway eventually stimulates a lower motor neuron The cell bodies of such higher motor neurons generally lie within the Central Nervous System, which is abbreviated as CNS The Central Nervous System (CNS) is the portion of the nervous system that is centrally located within the skull and the vertebral column Speci cally,
Central Nervous System Brain Spinal cord CNS
CHAPTER 14 Neuromuscular Connection
The brain is technically the upper portion of the CNS that lies within the skull The spinal cord, in contrast, is the narrow, cord -like lower portion of the CNS that is housed within the vertebral column Figure 1410 provides an overview of the CNS, along with the relative positions of the brain and spinal cord One especially important location for higher motor neurons in the brain is an area called the precentral gyrus (JEYE-rus) The name gyrus means ring or fold The precentral gyrus, therefore, is a raised ring or fold of brain tissue located just before or in front of (pre-) a groove called the central sulcus (SUL-kus) The precentral gyrus lies at the superior end of the cerebrum (seh-REEbrum) or main brain mass Since this gyrus is at the surface, it is part of the cerebral cortex (KOR-tex) or gray matter bark covering the main brain
Left precentral gyrus (primary motor area)
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