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CHAPTER 16 Blood and Circulatory System
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The Blood Connective Tissue
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Having discussed the heart as a pump and the blood vessels as tubes for carrying owing blood, it is now time to consider the blood itself Blood is a red, sticky, connective tissue that occupies about 5 6 liters (LEE-ters) of volume in an average-sized adult
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PLASMA
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At rst, it may seem odd to classify blood as a connective tissue After all, it contains no connective tissue bers (such as collagen or elastic bers) that directly strap body parts together Nevertheless, blood is considered a special connective tissue, because it contains plasma (PLAZ-muh) Plasma is the clear, watery, intercellular substance found between (inter-) the cells (cellul) of the bloodstream Because it circulates throughout the body within the bloodstream, plasma acts like a functional connective tissue rather than a structural one Recall that hormones ( 15), for instance, are First Messengers secreted by the endocrine glands and carried throughout the body within the bloodstream It is the plasma, not the blood cells per se, that does this functional connecting or carrying of the hormones towards their various target cells The plasma is basically a saline (SAY-leen) or salt -containing solution consisting of 09% NaCl (sodium chloride) solute ( 4) dissolved in water solvent In addition to carrying hormones, nutrients such as glucose and O2, and waste products like CO2, the blood also contains a number of important plasma proteins Some of these plasma proteins are critical for blood clotting Still others play a role in such processes as body defense from foreign invaders
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FORMED ELEMENTS IN THE BLOOD
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Besides the plasma, there are also many formed elements within the bloodstream Formed elements are cells and cell fragments within the blood that have a de nite shape or form When a sample of human blood is stained and viewed under a compound microscope (Figure 167), several major types of formed elements can be identi ed Most numerous among these are the erythrocytes (air-RITHroh-sights) or red (erythr) blood cells (cytes) Erythrocytes (red blood cells) are anucleate (ay-NEW-klee-aht); that is, they are without (a-) any
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PART 4 Anatomy and Physiology of Animals
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ERYTHROCYTES Hemoglobin molecules White (leuk) cytoplasm Purplish nucleus
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Leukocytes (WBCs)
Platelets ( little plates ) or thrombocytes
Fig 167 The major formed elements of the blood
nucleus They are also quite special in that they are shaped like biconcave (buy-KAHN-cave) discs, being caved-in on both (bi-) sides Viewed from the side, this makes them look like red hourglasses! The red color is mainly due to the presence of hemoglobin (HEE-moh-glohb-in) Hemoglobin is a reddish-colored, globe -shaped (glob), protein substance (-in) found within the cytoplasm of the red blood (hem) cells There may be as many as 10,000 hemoglobin molecules present within a single erythrocyte The main job of these thousands of hemoglobin molecules is carrying oxygen (O2) molecules through the bloodstream, and to the tissue cells Leukocytes (LEW-koh-sights) are the white (leuk) blood cells (cytes) These cells typically have a large, purplish-staining nucleus, but they are named for the clear, whitish appearance of their cytoplasm (This is in marked contrast, of course, to the red, hemoglobin-rich cytoplasm of the erythrocytes) The leukocytes have signi cant roles in protecting the body from various foreign invaders (Details are given in 17)
CHAPTER 16 Blood and Circulatory System
The third common formed element are the platelets (PLAY-teh-lets) or thrombocytes (THRAHM-buh-sights) The platelet name comes from their shape little plate -like fragments of disintegrated bone marrow cells The thrombocyte name derives from their function clotting (thromb) cells About 1/3 the size of an erythrocyte, the platelets (thrombocytes) are scattered here and there in small groups, throughout the plasma These purplishcolored, plate-like cell fragments have very sticky surfaces Thus, whenever a blood vessel ruptures and hemorrhages, the platelets soon collect around the open hole and stick to a network of thin, ber -like strands, composed of the protein, brin (FEYE-brin) As the platelets collect and stick to one another, a clot or thrombus (THRAHM-bus) is soon formed The hole is blocked, hemorrhaging stops, and wound healing follows
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