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Dextroamphetamine, for attention de cithyperactivity disorder, 512 DHE, for migraine, 154, 155 Diabetes insipidus (DI), 483 485 with head injury, 748 Diabetes mellitus, pupils in, 242 Diabetic acidosis, 966 Diabetic amyotrophy, 1135 1136, 1170 Diabetic neuropathy, 1134 1137 acute mononeuropathy, 1135 autonomic, 1135 1136 distal polyneuropathy, 1134 1135 multiple mononeuropathy and radiculopathy, 1135 pathology and pathophysiology of, 1136 treatment of, 1136 1137 Diabetic ophthalmoplegia, 1135 Diabetic radiculopathy, 1135 Diabetic retinopathy, 211 Dialysis dementia, 971 Dialysis disequilibrium syndrome, 970 971 Dialysis encephalopathy, 971 Diaminophenylhydrazine test, for metabolic defects, 801t Diazepam (Valium), 1023 for alcohol withdrawal, 1011 for pathologic alcohol intoxication, 1007 for seizures, 292t, 297 for stiff-man syndrome, 1279 DIC, stroke and, 737 Dichlorphenamide, for hypokalemic periodic paralysis, 1271 Diencephalic syndrome, 486 Diet, in epilepsy, 299 Differential xation, 500 Diffuse axonal injury, 751, 752, 755t Diffuse in ltrative lymphocytosis syndrome (DILS), in HIV/AIDS, 656 Diffusion-weighted imaging (DWI), 19 20 Dihydroergotamine (DHE), for migraine, 154, 155 2,3-Dimercaptopropanol, for lead poisoning, 1035 Diparesis, 505 Diphenhydramine (Benadryl), for extrapyramidal side effects, 1328 Diphosphonate, for myositis ossi cans, 1283 Diphtheria, 1031 1032 Diphtheric polyneuropathy, 1128 1129 Diplacusis, 249
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Diplegia, 50, 505 cerebrocerebellar, 879 spastic, 876 Diplomyelia, 861 Diplopia, 230 233 monocular, 233 in multiple sclerosis, 779 Dipyridamole, for atheroembolic infarction and transient ischemic attacks, 697 Disabling positional vertigo, 261, 263 Disconjugate gaze, 222 Disconnection syndromes, 389 390, 391f, 409 410 Discriminative sensation, testing of, 137 Disjunctive gaze, 222 Disorganized schizophrenia, 1321 Disseminated intravascular coagulation (DIC), stroke complicating, 737 Disseminated myoclonus, 174 Dissociated nystagmus, 238 Disul ram (Antabuse), peripheral neuropathy due to, 1133 1134 Divergence eye movements, 222 Divergence paralysis, 233 Dix-Hallpike maneuver, 262f Dizziness See also Vertigo with brain tumors, 553 de nition of, 256 psychiatric, 258 with stroke, 739 DJ-1, in Parkinson disease, 921 Docetaxel (Taxotere) intoxication, 1040, 1133 Doll s-head eye movements, 227 with brain herniation, 310 in comatose patient, 314 L-Dopa for Parkinson s disease, 921 922, 923 924 for progressive supranuclear palsy, 928 side effects of, 923 924 L-Dopa/carbidopa, for restless legs syndrome and periodic leg movements of sleep, 339 Dopamine, in basal ganglia, 59 60 Dopamine agonists, for Parkinson s disease, 922 Dopaminergic bers, 75 Dopa-responsive dystonia, 67 juvenile, 930 931 Dorsal horn, 113, 114f Dorsal midbrain syndrome, 227 Dorsal root ganglia, sensory syndromes involving, 139 140 See also Ganglionopathy; Neuronopathy
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Dorsal spinocerebellar tract, 71 Double athetosis, 65 Doublecortin mutations, 888 889 Down syndrome, 863 Alzheimer s disease and, 863, 906 Moyamoya and, 863 Downbeat nystagmus, 238 Doxycycline, for Lyme disease, 620 Dreaming function of, 337 338 nightmares and, 342 343 in REM and NREM sleep, 334 337 Dressing apraxia, 49, 401 Driving, epilepsy and, 298 299 Droopy shoulder syndrome, 186 Drop attacks, 329 seizures versus, 287 syncope versus, 329 TIA versus, 692 Drowsiness, 304 See also Sleepiness after head injury, 754 Drugs See also speci c drugs and drug types bioavailability of, 1017 disorders due to, 1016 1030 with antidepressants, 1026 1028 with antipsychotics, 1024 1026 chorea, 64 65 confusional states, 362 363 delirium, 362 363 encephalopathies, aggressive behavior in, 448 fatigue, 435 with hallucinogens, 1028 1030 myasthenic weakness, 1262 myopathies, 1238 1239, 1240t 1241t, 1242 neuropharmacology and, 1016 1017 with opiates and synthetic analgesics, 1017 1021 peripheral neuropathy, 1133 1134 with sedative-hypnotics, 1021 1024 seizures, 290 291 with stimulants, 1028 interactions with nervous system, 1016 1017 Drunken gait, 103 Drusen, 209 Duane retraction syndrome, ophthalmoplegia in, 235 Duchenne muscular dystrophy, 1214t, 1214 1215, 1216f, 1216 1217 Duck embryo vaccine (DEV), 641 Dural stula, cerebral, 725 Dural stulas, spinal, 1070 Dural sinus thrombosis, 734 735 Dural tear myelopathy, 1079 Duret hemorrhage, 752
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INDEX
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Dwar sm, 857 858 nanocephalic (Seckel bird-headed dwar sm), 857 Dynorphin, 118 Dysarthria, 417, 426 427 pseudobulbar, 426 427 scanning, 77 slurring, 77 spastic, 426 427 Dysautonomia in Guillain-Barre syndrome, 1122 inherited, 464 paraneoplastic, 586 Riley-Day, 200, 464, 1159 1160 Dysautonomic cephalalgia, posttraumatic, 158 Dysautonomic polyneuropathy, 462 463 Dyscalculia, 402, 899 developmental, 511 Dyschondroplasia, 856 Dyscognitive state, 277 Dysdiadochokinesis, 76 Dysembrioblastic neuroepitheliomas, 570 Dysesthesia, 134 de nition of, 118t in peripheral nerve disease, 1114 1115 Dysferlin, 1216t, 1223 Dysgraphia, developmental, 511 Dyskinesia, 64, 67 kinesigenic, paroxysmal, 68 myoclonic jerks in sleep and, 339 with phenothiazines, 1025 Dyslalia, 509 Dyslexia, developmental, 510 511 Dysmetria, 76 Dysnomia, 900 Dysosmia, 198 199 Dysphagia, 476, 477 with stroke, 738 Dysphasia See Aphasia Dysphonia, 417, 427 428 spasmodic, 91, 428 429 Dysphoric symptoms, in opioid addiction, 1019 Dyspnea, 475 Dysraphism, 859f, 859 861 Dyssynergia, 75, 76 Dystasia, are exic, hereditary, 1157 Dystonia, 66f, 66 67 acute generalized dystonic reactions, 67 cervical, idiopathic, 91, 92f, 93 dopa-responsive, 67 juvenile, 930 931 hereditary, 931 with hereditary metabolic disease, 834 836
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identity with athetosis and chorea, 68 69 occupational, 94 oromandibular, 91 paroxysmal, nocturnal, 342 paroxysmal choreoathetosis and, 68 periodic, 68 with phenothiazines, 1025 rapid-onset dystonia-parkinsonism, 67 symptomatic (secondary), 91 Dystonia musculorum deformans, 929 930 Dystonia-parkinsonism, hereditary, 930 931 Dystonic gait, 102t, 104 105 Dystonic tremor, 84 Dystroglycan, 1216 Dystrophia myotonica, 1221 1223 Dystrophinopathies, 1213, 1214t, 1216 E Eastern equine encephalitis, 637 Eaton-Lambert syndrome See LambertEaton myasthenic syndrome Echinococcosis, myopathy associated with, 1203 Echo speech, 502 Echolalia, 417, 899 Echovirus, 633 Eclampsia hypertensive encephalopathy in, 729 seizures in, 291 Edinger-Westphal nucleus, 241, 241f Edrophonium test, in myasthenia gravis, 1254 1255 Ehlers-Danlos syndrome, stroke and, 705 Ejaculation, 470 Elation, 450 Elderly people autonomic failure in, 464 chronic mild sensory polyneuropathy in, 1151, 1151t falls in, 521 gait of, 102t, 106 107, 107f headaches in, 157 158 polyneuropathy in, 1151 seizures in, 291 292 Electrical injuries, of spinal cord, 1056 1057 Electrocerebral silence, 28 Electroconvulsive therapy (ECT), for depression, 1315 Electroencephalography (EEG), 23 24, 25f 27f abnormal recordings on, 27 29 minor, clinical signi cance of, 29 neurologic conditions with, 28 29
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age-related changes in, 523 consciousness alterations and, 307 in epilepsy, 283 284 normal recordings on, 24 26 occipital driving response in, 30 in pediatric patients, 25 26 Electrolyte balance disorders of See also speci c disorders muscle and, 1096 seizures due to, 290 neuromuscular activity and, 1092 1093 Electromyography (EMG), 1101 1106, 1102f abnormalities on, 1102 1105, 1103f 1105f single- ber, 1106 in myasthenia gravis, 1254 Electronystagmography, 260 Electro-olfactography (EOG), 196 Electrophysiologic testing, 142 See also speci c techniques in myasthenia gravis, 1254 Embolic infarction, 700 704, 701t clinical picture in, 702f, 702 703 course and prognosis of, 703 laboratory ndings in, 703 treatment and prevention of, 703 704 Embolism, brocartilaginous, 1072 Embryonal period, 493 Emergency reactions, 458 459 Emery-Dreifuss muscular dystrophy, 1217, 1217f Emotional disturbances See also Psychiatric disorders; speci c disorders in acute confusional states, 358 acute fear, anxiety, elation, and euphoria and, 449 450 aggressiveness, anger, rage, and violence and, 446 448 altered sexuality and, 449 differential diagnosis of, 450 disinhibition of emotional expression, 445 446 in hallucinating and deluded patients, 444 445 placidity and apathy and, 448 449 with temporal lobe lesions, 399 Emotional lability, 445 446 Empty delta sign, 734 Empty sella syndrome, 577 Empyema, subdural, 603 604 Encephalitis bacterial See Bacterial encephalitis brainstem, paraneoplastic, 585 EEG in, 28
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