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Omega-3 Fatty Acids
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Interest in omega-3 fatty acids began 30 years ago, when it was discovered that the Inuit population of Greenland had low rates of cardiovascular disease, despite consuming a high protein and high fat diet (mostly in form of fish) Evidence from multiple large-scale observational studies and randomized controlled trials indicates that intake of fish or fish oil supplements (or both) containing the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is associated with many health benefits A recent review concluded that modest consumption of fish (1 2 servings per week), especially species higher in the omega-3 fatty acids EPA and DHA, reduces the risk of coronary death by 36% and total mortality by 17% Multiple mechanisms have been proposed for the beneficial effects of omega-3 fatty acids for both primary and secondary prevention of cardiac disease These include reductions in triglyceride levels, inflammation, blood pressure (2 5 mm Hg), blood clotting, arrhythmias, and atherosclerotic plaque formation The reduction in triglyceride levels appear to be dose-dependent, with effects at doses as low as 2 g/d Higher doses have greater effects, and 4 g/d can lower triglyceride levels by 25 40% Several well-conducted, randomized controlled trials report that in individuals with a history of heart attack, regular consumption of oily or fish oil/omega-3 supplements reduces the risk of nonfatal heart attack, fatal heart attack, sudden death, and all-cause mortality Benefits have been reported beginning after 3 months of use, and for as long as 35 years of follow-up Animal sources of omega-3 fatty acids (EPA and DHA) include fish, especially cold-water fatty fish such as salmon, mackeral, halibut, anchovies, and sardines Vegetable sources of the omega-3 fatty acid alpha-linolenic acid (ALA) include English walnuts; flaxseeds; tofu/soy and some vegetable oils, such as canola, soy, flaxseed, and olive oil Dietary intake of omega-3 fatty acids has declined by 80% over the past century, while intake of omega-6 fatty acids has greatly increased Omega-6 fatty acids come from the common use of other vegetable oils (corn, safflower, and sunflower oils) containing linoleic acid; these compete with omega-3 fatty acids to be converted to active pro-inflammatory metabolites in the body In 2003, the American Heart Association recommended that healthy people eat fish at least twice a week as well as consume plant-derived sources of omega-3 fatty acids, such as tofu/soybeans, walnuts, flaxseed oil, and canola oil People with known coronary heart disease should take in approximately 1 g/d of EPA and DHA (combined) The FDA regards intake of up to 3 g/d of omega-3 fatty acids from fish as safe Fish oil supplements are widely available over the counter and should be dosed based on their content of EPA and DHA Omega-3 fatty acid 1 g prescription capsules, containing 465 mg of EFA and 375 mg of DHA, are also FDA-approved for the treatment of hypertriglyceridemia The most common side effects of fish oil supplementation are gastrointestinal upset, burping, fishy taste, loose stools, and nausea High doses may also have harmful effects, such as an increased risk of bleeding, so the FDA recommends no more than 3 g of EPA plus DHA per day and no more than 2 g from the diet The potential for harm from mercury, dioxins, and polychlorinated biphenyls (PCBs) present in some fish was
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In acupuncture, anatomic points on the surface of the body are stimulated by a variety of techniques, often with needles, to treat illness and promote health Many styles exist and are practiced as part of the medical traditions of China, Japan, Korea and other countries Practitioners trained in Oriental medicine believe that a vital energy called chi (pronounced chee ) circulates in the body through 12 virtual pathways called meridians Disease occurs when the flow of chi in the body is not in balance Each meridian is named after a particular organ or official, but the term actually relates to the energetic function, in addition to the structure or anatomy of the organ There are both surface and internal projections for each meridian The surface projections contain sites called acupuncture points
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