Infectious Diseases in .NET framework

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the body that lies deep under the surface of the skin [Study suggestion: It is highly recommended that you follow up this idea with a careful reading of both ANATOMY DEMYSTIFIED and PHYSIOLOGY DEMYSTIFIED, which quite creatively carry out Galileo s geometric view of human body structure and function!]
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Discovering animalcules : A Dutchman creates the science of microbiology
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About a century after Galileo, an uneducated Dutchman named Anton van Leeuwenhoek (LOO-en-hohk) began grinding glass lenses in his spare time Leeuwenhoek earned his living as a linen draper This is a person who uses linen from the stems of the ax plant (which has thin, threadlike parts) to sew cloth fabrics, such as drapes Leeuwenhoek probably began grinding his glass lenses to help him magnify and clearly see the intricate (and nearly microscopic) geometric patterns of crisscrossing linen threads in his fabrics One common pattern of fabric studied by Leeuwenhoek is shown in Figure 32 (A) This intricate crisscrossing pattern creates a rectangle-shaped matrix (MAY-tricks) or womb The matrix (womb) is frequently used as a basic model for reproducing more complicated geometric designs [Thinking suggestion: What is a possible connection between this matrix pattern of woven cloth fabrics and the rectangular Memory Pillboxes used to store key text facts at the end of each chapter in this book Explain, and then discuss your insights with a friend!] Like Galileo before him, Leeuwenhoek apparently concluded that, The Book of Nature is written in characters of Geometry He was referring, in particular, to the microscopic world of the rectangular thread matrix! Getting very excited about studying microscopic objects, he developed a keen interest in closely examining a wide variety of both living and nonliving things In the early years, he used a cumbersome handheld device, but with later re nement, Leeuwenhoek developed the rst stand-up microscope (Figure 32, B) In one instance, he put a drop of greenish-looking pond water under the lenses of his microscope Leeuwenhoek was amazed to see hundreds of what he called animalcules (AN-ih-mal-kyools), or tiny (-cules) greenish-yellow animals, busily swimming around! In modern terminology, these animalcules are called the protozoa (proh-toh-ZOH-ah) the rst or most primitive (proto-) types of animals (zoa) These protozoa are living organisms, but they are extremely small, because in most cases their whole body is unicellular This
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PART 1
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Woven cloth fabric
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Foundations
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(A) Criss-crossing matrix or "womb" of linen threads
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"Animalcules" (Protozoa) on slide
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(B) Leeuwenhoek looks through his stand-up microscope
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Fig 32 Leeuwenhoek and his world of the microscope
means that their body consists of just one (uni-) living little cell (cellul) [Study suggestion: Using your prior knowledge, try to build a single term that means one who specializes in the study of the most primitive animals Check your answer with the text that follows] Later, Leeuwenhoek also discovered bacteria in various places, such as in the scum covering the teeth in his own mouth! Therefore, we can call Leeuwenhoek the rst protozoologist (proh-toh-zoh-AHL-uh-jist), because he studied primitive animals Likewise, Leeuwenhoek was the rst bacteriologist (bakteer-e-AHL-oh-jist) After all, he was a specialist in studying (-ologist) the bacteria The word, bacteria (bak-TEER-e-uh), literally translates to mean little staffs, clubs, or rods (bacteri) that are present (-a) Figure 33 provides an overview of the major types of bacteria [Study suggestion: Name the major types of bacteria that you think look most like little rods or clubs ]
Fig 33 The compound microscope used to view some major types of bacteria
(A) Baby Heinie gazing through a modern compound microscope (B) Some major types of bacteria that can be seen through a compound microscope
PART 1
Foundations
Each bacterium is just a single unicellular plant-like microorganism (MYkroh-OR-gah-nizm) present (-um) As shown in Figure 33, the bacteria include these types: the cocci (COCK-see), which look like round berries ; the bacilli (bah-SIL-ee), which resemble slender rods ; the spirochetes (SPY-rohkeets), named for their likeness to tiny coiled hairs ; and the spirilla (spy-RILuh), which look like tight coils Observe from Figure 33 that Baby Heinie (a mischievous character who appears in both ANATOMY DEMYSTIFIED and PHYSIOLOGY DEMYSTIFIED) is standing upon a chair and looking at the different types of bacteria through a modern compound microscope Unlike the very simple microscopes developed by Leeuwenhoek, the compound microscope has the magni cation of the single lens in its main tube compounded or made better by additional lenses in the eyepieces This compounded effect allows the modern microscopist (like mischievous little Baby Heinie) to view objects such as bacteria more readily They can be magni ed from about 100 to 1,000 times their actual size
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