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PATHOGENIC MACROSCOPIC (GROSS) ORGANISMS
We have been discussing various types of microscopic organisms, especially those that may be pathogenic (path-oh-JEN-ik), that is, disease (path)
PART 1
Foundations
producing (gen) Many bacteria, for example, are pathogens (PATH-oh-jens) or disease producers in humans Each bacterium, of course, is only a single cell speci cally, a unicellular organism The pathogenic bacteria, therefore, that consist of just single cells (or relatively small groups of cells) are all microscopic Most gross (macroscopic) organisms, in dramatic contrast, are multicellular (mul-tih-SEL-yew-ler) creatures The human body is a well-known multicellular organism, because it consists of many (multi-) little cells (cellul) A great number of pathogenic organisms (pathogens) are also multicellular Hence, they are visible to our naked eyes Consider the nematodes (NEM-uh-toads), a large group of roundworms that are named for the fact that their multicellular bodies are shaped (-ode) like long, slender threads (nemat) The common earthworm burrowing through the moist soil of your garden is a nematode familiar to most of us [Study suggestion: Using the pre x non-, build a single term that means not causing disease Check your term with the one that follows in the text] The common earthworm is a nonpathogenic (NAHN-pah-thoh-JEN-ik) nematode, because it does not (non-) cause any human diseases There are, however, a number of nematodes that are pathogenic to humans! These include the hookworm, technically known as Ancylostoma (an-suh-LAHS-tuh-muh) This name literally means bent or crooked (Ancyl) mouth (stom) When a person walks barefoot on feces-contaminated soil, the soil may contain hookworm larvae (LAR-vee), immature hookworms These can burrow through the skin on the sole of the foot, causing ground-itch The larvae travel through the person s bloodstream and then migrate to the lungs Above the lungs, they crawl up the person s windpipe and are eventually swallowed! After passing through the stomach, the larvae mature and attach to the lining of the person s small intestine With their bent, hook-like mouths, these parasitic worms eagerly suck the blood of their unwilling human host! The medical term for this condition is ancylostomiasis (an-suh-lahs-tuhMY-uh-sis) The suf x, -iasis, means abnormal condition of [Study suggestion: Using your knowledge, translate ancylostomiasis into its common English equivalent Check your answer with the next sentence] Technically speaking, ancylostomiasis is an abnormal condition of hookworm infestation (in-fes-TAY-shun) An infestation is an attack by macroscopic animal parasites, such as nematodes
PATHOGENIC FUNGI: THEY RE NOT ALL JUST MUSHROOMS!
Earlier, we learned about infections, which are caused by pathogenic unicellular microbes such as bacteria And we have just learned about infestations,
Infectious Diseases
which are caused by pathogenic, multicellular, macroscopic organisms such as the hookworm What about the pathogenic fungi (FUN-jeye) the inquiring mind might well ask My doctor recently told me that I had a yeast fungus (FUN-gus) infection But aren t mushrooms in the woods also fungi Now, we can t see yeast cells with our naked eyes, but we can certainly go mushroom hunting! If parasitic fungi cause disease in our bodies, should these diseases be called fungal (FUN-gal) infections, or should they be called fungal infestations Good question! But the answer is simply, It depends The fungi, you see, are a large group of plantlike, vegetable organisms that either live on decaying organic matter or are parasites of living plants or animals The word fungus actually means presence of (-us) a mushroom (fung) But as Figure 35 shows, the kingdom Fungi consists of the unicellular yeasts, plus the multicellular molds and mushrooms When a woman has many vaginal (VAH-jih-nal) yeast cells, for instance, this is a type of fungal infection, since the yeast cells are microscopic parasites Attacks by other, larger, grossly visible multicellular fungi may result in a fungal infestation of the skin or other body organ But whether the invading fungus is unicellular and microscopic, or multicellular and macroscopic, it still results in a mycosis an abnormal condition (-osis) caused by a parasitic fungus (myc)
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