asp.net barcode reader sdk PART 4 in .NET

Generation European Article Number 13 in .NET PART 4

PART 4
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Moving Our Blood and Air
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Lumen
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Enlarging atheromas in left coronary artery progressively reduce heart muscle blood flow
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Atheroma enlarges to create severe acute myocardial ischemia ("heart attack")
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Nearly complete occlusion (blockage) of coronary artery lumen
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Area of myocardial necrosis results (myocardial infarction or MI)
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Fig 817 The sequence of events in CAD leading to a heart attack
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The Blood and Its Disorders
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The last major part of the circulatory (cardiovascular system) is the blood connective tissue Blood is a red, sticky connective tissue with a uid intercellular substance called the plasma It occupies about 4 to 6 liters of volume in the average-sized adult
Heart, Blood Vessel Disorders
Erythrocytes or r Red blood cells (hematocrit) containing hemoglobin
Fig 818 General components of the blood when it is centrifuged
THE HEMATOCRIT AND ERYTHROCYTES (RBCs)
Figure 818 shows how the blood separates when it is placed into a test tube and spun around by means of a centrifuge (SEN-trih-fyooj) machine At the bottom of the test tube we nd the heaviest component, called the hematocrit (he-MAT-oh-krit) The hematocrit consists of thousands of erythrocytes (airITH-roh-sights) or red (erythr) blood cells (cytes) The erythrocytes look red because of their high concentration of hemoglobin (HEE-moh-glohb-in) The hemoglobin molecule is a reddish-colored, globe (glob) -shaped protein (-in) present within red blood (hem) cells Each hemoglobin molecule, in turn, can carry up to four oxygen molecules (O2 ) through the bloodstream, and towards the oxygen-hungry tissue cells
PART 4
Moving Our Blood and Air
RBCs or ERYTHROCYTES ("Red cells") Red h molecules
or "white cells"
("clot cells")
Fig 819 The major types of formed elements in the blood
How about a closer look at the erythrocytes or RBCs (red blood cells), Noble Hippocrates the knowledge-thirsting modern reader may ask of our ancient host This closer look is provided by Figure 819, which displays the so-called formed elements (cells and cell fragments) present within the blood Observe that each RBC is indented on both sides, giving it an unusual hourglass shape One major disorder of the erythrocytes is various types of anemia (ah-NEEMe-uh) Taken literally, an anemia is a condition (-ia) without (an-) enough red blood (em) cells One common type is iron-de ciency anemia Each hemoglobin molecule contains four iron atoms, each of which can carry one oxygen molecule (O2 ) One human RBC holds 200 to 300 million molecules of hemoglobin, so that s a lot of iron contained in the hemoglobin! Therefore, when a person has a chronic bleeding, they lose thousands of RBCs along with billions of hemoglobin molecules containing iron The result is an iron de ciency within the bloodstream and a greatly reduced energy
Heart, Blood Vessel Disorders
level This weakness is caused by an inability to transport much oxygen through the bloodstream In women, one type of excessive bleeding is a heavy menstrual (MEN-stroo-al) or monthly loss from the vagina In both sexes, chronic gastrointestinal (gas-troh-in-TES-tih-nal) bleeding from the stomach (gastr) and intestines (intestin) can be due to a bleeding ulcer
THE BUFFY COAT
A look back at Figure 818 shows a thin, milky buffy coat in a centrifuged test tube This layer contains the leukocytes and the platelets (PLAY-teh-lets) or thrombocytes (THRAHM-buh-sights) Review of Figure 819 reveals that the leukocytes are called white (leuk) blood cells because of the clear, whitish appearance of the cytoplasm around their purplish nuclei The platelets get their name from their resemblance to little plates here and there within the bloodstream The platelets carry the alternate physiological name of thrombocytes because their cell membranes are sticky and they collect together and help create thrombi (blood clots) You may remember from our discussion of the immune-lymphatic system ( 5) that the various types of leukocytes play important roles in body defense from foreign invaders (antigens) Hence, consider a clinical problem such as leukocytopenia (loo-koh-sigh-toh-PEEN-ee-ah) This is a poverty of (-penia) white (blood) cells (leukocyt) within the bloodstream There should normally be about 10,000 leukocytes present in every cubic millimeter of blood When there are fewer than half this number (5,000 leukocytes per cubic millimeter), then leukocytopenia exists With so few leukocytes circulating, the body is much more prone to suffer various diseases and infections As far as platelets (thrombocytes) are concerned, they, too, must be present in suf cient numbers within the bloodstream If they are greatly reduced in number, then blood clotting will be very show after a vessel is cut As a result, the person may hemorrhage to death! (This stark fact explains why the platelets are alternately called thrombocytes or clot -making cells )
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