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F R + S 180 L/day 179 L/day a few mL/day (filtered) (reabsorbed) (secreted)
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The urinary pathway
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After the urine is formed within the two kidneys millions of nephrons, it enters the urinary pathway The urinary pathway starts with the urine constantly dripping through the renal pyramids of the renal medulla and then
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Bottom tip of a renal pyramid Urine droplets A renal calyx
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Like miniature sprinkling cans
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"Kidney flower cup"
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Ureter Body of renal pelvis (within a kidney)
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Fig 135 The renal calyces as a bouquet of ower cups
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Fig 136 The urinary pathway
down into the renal calyces (KAY-lih-sees) These are literally the kidney ower cups Shown in less detail back in Figure 131, but in more detail in Figure 135, the renal calyces are the expanded, hollow, ower cup like extensions of the renal pelvis Like water from the spouts of miniature sprinkling cans, drops of urine constantly fall through tiny holes in the tip of each renal pyramid The urine is received by the indented ower cup of each renal calyx (KAY-licks) Perhaps we might visualize the whole group of renal calyces as a striking bouquet of ower cups with wide, hollow stems These stems eventually merge to create the body (central portion) of the bowl-like renal pelvis The urine immediately pools within the body of the renal pelvis, then leaves each kidney through a ureter (YUR-eh-ter) The ureter is a muscle-walled tube that constricts and milks urine out of the renal pelvis Both the right and left ureters travel down into the waiting urocyst (YUR-oh-sist) or urinary (ur) bladder (cyst) (View Figure 136) The urocyst (urinary bladder) is a hollow, muscle-walled pouch that temporarily stores the urine produced by both kidneys Below the urocyst lies the urethra (you-REETH-rah) the tube that a person uses to make water (urethr) by urinating When the urinary sphincter around the urethra voluntarily relaxes, the stored urine passes out of the urocyst It ows through the urethra,
PART 6
Life in Land Down Under
and then exits from the body via the urinary ori ce (OR-ih- s) This is a tiny, mouth (or) -like opening for excreting the urine
Some urinary disorders
There are two different (but often closely related) basic types of urinary disorders: (1) physiological disorders of urine formation or excretion; and (2) anatomical disorders of the urinary pathway Perhaps the most common urinary disorder is diuresis [Memory probe: Do you remember the meaning of this term It was mentioned in 10 as one of the major symptoms of diabetes mellitus Speculate, then read on!] Diuresis, you may recall, is a process of (-esis) too much urine (ur) passing out through (di-) the body A close synonym of diuresis is polyuria (pahl-ee-YUR-ee-ah) Polyuria is literally a condition of (-ia) much (poly-) urine (ur) We might think of polyuria (diuresis) as a urinary ltration (F) or a tubular reabsorption (R) problem A basic outline of an excessive urinary ltration problem is as follows:
Excessive ingestion of fluids Excessive blood volume Excessive BP
Polyuria (excessive urination)
Excessive F
[Memory probe: 8, which discussed the circulatory (cardiovascular) system, included technical terms for condition of de cient blood volume, which is / / , and condition of excessive (blood) pressure, which is / / Try to ll in the word parts of these subdivided medical terms] It is normal for an excessive intake of uid to trigger polyuria, since so much added body water results in a temporary hypervolemia (high-per-voh-LEE-meah) Hypervolemia, of course, is a condition of excessive (blood) volume This hypervolemia, in turn, creates a temporary hypertension The high blood volume exerts a greater pushing force upon the vessel walls In normal, healthy kidneys, however, there is a very ef cient renal compensation or process of making up for these temporary physiological disorders There is simply a greater amount of urinary ltration (F) of uid out of the bloodstream and into the kidney tubules The excess uid is excreted in the urine, creating diuresis (polyuria) As a result, normovolemia and normotension are soon re-attained Another type of cause for polyuria, though, involves great de ciencies in tubular reabsorption (R) of water Many types of renal diseases interfere with the
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