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Or a cro nge ssv , ein s Or an cro ge ssv , ein les s Re d, cro ssv ein s Re d cro ssv ein les s
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Parents a. Orange, crossveins orange, crossveins b. Red, crossveins red, crossveinless c. Red, crossveinless red, crossveins d. Red, crossveins red, crossveins
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Cross a. Yellow, tall yellow, tall b. Yellow, short yellow, short c. Green, tall yellow, short
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28. A brown-eyed, long-winged y is mated with a redeyed, long-winged y. The progeny are
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What are the genotypes of the parents
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33. In Drosophila melanogaster, a recessive autosomal gene, ebony, produces a dark body color when homozygous, and an independently assorting autosomal
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Tamarin: Principles of Genetics, Seventh Edition
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II. Mendelism and the Chromosomal Theory
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2. Mendel s Principles
The McGraw Hill Companies, 2001
Two Mendel s Principles
gene, black, has a similar effect. If homozygous ebony ies are crossed with homozygous black ies, a. what will be the phenotype of the F1 ies b. what phenotypes and what proportions would occur in the F2 generation c. what phenotypic ratios would you expect to nd in the progeny of the backcrosses of F1 ebony F1 black 34. A, B, and C are independently assorting Mendelian factors (genes) controlling the production of black pigment in a rodent species. Alleles of these genes are indicated as a, b, and c, respectively. Assume that A, B, and C act in this pathway: colorless control by A red Z control by C black control by B Y red
37. When studying an inherited phenomenon, a geneticist discovers a phenotypic ratio of 9:6:1 among offspring of a given mating. Give a simple, genetic explanation for this result. How would you test this hypothesis 38. You notice a rooster with a pea comb and a hen with a rose comb in your chicken coop. Outline how you would determine the nature of the genetic control of comb type. How would you proceed if both your rooster and hen had rose combs 39. Suggest possible mechanisms for the epistatic ratios given in table 2.4. Can you add any further ratios 40. What are the differences among dominance, epistasis, and pleiotropy How can you determine that pleiotropic effects, such as those seen in sickle-cell anemia, are not due to different genes 41. You are working with the exotic organism Phobia laboris and are interested in obtaining mutants that work hard. Normal phobes are lazy. Perseverance nally pays off, and you successfully isolate a truebreeding line of hard workers. You begin a detailed genetic analysis of this trait. To date you have obtained the following results: nonworker Z all nonworkers of both sexes F1: F1 female worker male Z 3/4 hard workers:1/4 nonworkers of both sexes From these results, predict the expected phenotypic ratio from crossing two F1 nonworkers.
BIOCHEMICAL GENETICS
colorless
A black AA BB CC individual is crossed with a colorless aa bb cc to give black F1 individuals. The F1 individuals are selfed to give F2 progeny. a. What proportion of the F2 generation is colorless b. What proportion of the F2 generation is red 35. In a particular Drosophila species, there are four strains differing in eye color: wild-type, orange-1, orange-2, and pink. The following matings of truebreeding individuals were performed.
Cross wild-type orange-1 wild-type orange-2 orange-1 orange-2 orange-2 pink F1 (orange-1 orange-2) pink F1 all wild-type all wild-type all wild-type all orange-2 1/4 orange-2: 1/4 pink:1/4 orange-1: 1/4 wild-type
hard worker
42. The following is a pathway from substance Q to substance U, with each step numbered: 1 2 3 4 Q R S T U Which product should build up in the cell and which products should never appear if the pathway is blocked at point 1 At 2 At 3 At 4 43. The following chart shows the growth ( ) or lack of growth ( ) of four mutant strains of Neurospora with various additives. The additives are in the pathway of niacin biosynthesis. Diagram the pathway and show which steps the various mutants block. Which compound would each mutant accumulate When you complete this problem, compare your results with gure 2.27. What effect on growth would you observe following a mutation in the pathway of serine biosynthesis
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