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CHROMOSOMES
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1. What are the major differences between prokaryotes and eukaryotes 2. What is the difference between a centromere and a kinetochore 3. What is the difference between sister and nonsister chromatids Between homologous and nonhomologous chromosomes 4. In human beings, 2n 46. How many chromosomes would you nd in a a. brain cell d. sperm cell b. red blood cell e. secondary oocyte c. polar body
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(See also MEIOSIS IN ANIMALS) MITOSIS
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5. You are working with a species with 2n 6, in which one pair of chromosomes is telocentric, one pair subtelocentric, and one pair metacentric.The A, B, and C loci, each segregating a dominant and re*Answers to selected exercises and problems are on page A-3.
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cessive allele (A and a, B and b, C and c), are each located on different chromosome pairs. Draw the stages of mitosis. 6. Identify stages a f in the nuclear division shown in gure 1 (on the next page). Include the process, stage, and diploid number (e.g., meiosis I, prophase, 2n 10). Keep in mind that one picture could represent more than one process and stage. Chromosomes are drawn as threads, with circles representing kinetochores. (See also MEIOSIS) 7. When during the cell cycle does chromosome replication take place 8. A mature human sperm cell has c amount of DNA. How much DNA (c, 2c, 4c, etc.) will a somatic cell have if it is in a. G1 b. G2 How much DNA will be in a cell at the end of meiosis I
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Tamarin: Principles of Genetics, Seventh Edition
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II. Mendelism and the Chromosomal Theory
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3. Mitosis and Meiosis
The McGraw Hill Companies, 2001
Three
Mitosis and Meiosis
MEIOSIS
9. Given the same information as in problem 5, diagram one of the possible meioses. How many different gametes can arise, absent crossing over What variation in gamete genotype is introduced by a crossover between the A locus and its centromere 10. How many bivalents, tetrads, and dyads would you nd during meiosis in human beings in fruit ies in the other species of table 3.3 11. Can you devise a method of chromosome partitioning during gamete formation that would not involve synapsis that is, can you reengineer meiosis without passing through a synapsis stage 12. What are the differences between a reductional and an equational division What do these terms refer to 13. How does the process of meiosis explain Mendel s two rules of inheritance 14. Drosophila has four pairs of chromosomes. Let chromosomes from the male parent be A, B, C, and D, and
those from the female parent be A , B , C , and D . What fraction of the gametes from an AA BB CC DD individual will be a. all of paternal origin b. all of maternal origin c. half of maternal origin and half of paternal origin 15. Wheat has 2n 42 and rye has 2n 14 chromosomes. Explain why a wheat-rye hybrid is usually sterile. 16. The arctic fox has fty small chromosomes, and the red fox has thirty-eight larger chromosomes. Hybrids of these two species are sterile, but cytological studies during meiosis in these hybrids reveal both paired and unpaired chromosomes. a. Account for the sterility of the hybrids. b. How can you explain the paired chromosomes 17. An organism has six pairs of chromosomes. In the absence of crossing over, how many different chromosomal combinations are possible in the gametes
(c) Figure 1
Stages in nuclear division.
Tamarin: Principles of Genetics, Seventh Edition
II. Mendelism and the Chromosomal Theory
3. Mitosis and Meiosis
The McGraw Hill Companies, 2001
Critical Thinking Questions
MEIOSIS IN ANIMALS
18. How many sperm come from ten primary spermatocytes How many ova from ten primary oocytes 19. How do the quantity of genetic material and the ploidy change from stage to stage of spermatogenesis and oogenesis (see gs. 3.28 and 3.29) (Consider the spermatogonium and the oogonium to be diploid, with the chromosome number arbitrarily set at two.) 20. How many sperm cells will form from a. fty primary spermatocytes b. fty secondary spermatocytes c. fty spermatids 21. In human beings, how many eggs will form from a. fty primary oocytes b. fty secondary oocytes
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