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The McGraw Hill Companies, 2001
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F-duction See sexduction. fecundity selection The forces causing one genotype to be more fertile than another genotype. feedback inhibition A posttranslational control mechanism in which the end product of a biochemical pathway inhibits the activity of the rst enzyme of the same pathway. fertility factor The plasmid that allows a prokaryote to engage in conjugation with, and pass DNA into, an F cell. F factor See fertility factor. lial generation Offspring generation. F1 is the rst offspring, or lial, generation; F2 is the second; and so on. mbriae See pili. rst-division segregation (FDS) The allelic arrangement of ordered spores that indicates the lack of recombination between a locus and its centromere. tness, W The relative reproductive success of a genotype as measured by survival, fecundity, or other life-history parameters. 5 untranslated region (5 UTR) See leader. oral meristem The shoot apical meristem sets aside this tissue that gives rise to owers. oral-meristem identity genes At least ve genes known to establish the identity of the oral meristem. uctuation test An experiment by Luria and Delbr ck that compared the variance in number of mutations among small cultures with that among subsamples of a large culture to determine the mechanism of inherited change in bacteria. uorescent in situ hybridization (FISH) A technique in which a uorescent dye is attached to a nucleotide probe that then binds to a speci c site on a chromosome and makes itself visible by its uorescence. Fokker-Planck equation An equation that describes diffusion processes. It is used by population geneticists to describe random genetic drift. footprinting A technique to determine the length of nucleic acid in contact with a protein. While in contact, the free DNA is digested. The remaining DNA is then isolated and characterized. founder effect Genetic drift observed in a population founded by a small, nonrepresentative sample of a larger population. F-pili Sex pili. Hairlike projections on an F+ or Hfr bacterium involved in anchorage during conjugation. fragile site A chromosomal region that has a tendency to break. fragile-X syndrome The most common form of inherited mental retardation. Named for its association with an X chromosome with a tip that breaks or appears uncondensed. Inheritance involves imprinting.
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frameshift A mutation in which there is an addition or deletion of nucleotides that causes the codon reading frame to shift. free energy of activation ( G ) Energy needed to initiate a chemical reaction. frequency-dependent selection A selection whereby a genotype is at an advantage when rare and at a disadvantage when common. functional alleles Mutations that fail to complement each other in a cis-trans complementation test. fundamental number (NF) The number of chromosome arms in a somatic cell of a particular species. gamete A germ cell having a haploid chromosomal complement. Gametes from parents of opposite sexes fuse to form zygotes. gametic selection The forces acting to cause differential reproductive success of one allele over another in a heterozygote. gametophyte The haploid stage of a plant life cycle that produces gametes (by mitosis). It alternates with a diploid, sporophyte generation. G-bands Eukaryotic chromosomal bands produced by treatment with Giemsa stain. gene Inherited determinant of the phenotype. See cistron; locus. gene ampli cation A process or processes by which the cell increases the number of repeats of a particular gene within the genome. gene cloning Production of large numbers of a piece of DNA after that piece of DNA is inserted into a vector and taken up by a cell. Cloning occurs as the vector replicates. gene conversion In Ascomycete fungi, a 2:2 ratio of alleles is expected after meiosis, yet a 3:1 ratio is sometimes observed. The gene conversion mechanism is explained by repair of heteroduplex DNA produced by recombination. gene family A group of genes that has arisen by duplication of an ancestral gene. The genes in the family may or may not have diverged. gene ow The movement of genes from one population to another by interbreeding between individuals in the two populations. gene pool All of the alleles available among the reproductive members of a population from which gametes can be drawn. generalized transduction Form of transduction in which any region of the host genome can be transduced. See specialized transduction. general transcription factors Eukaryotic proteins that form part of the RNA polymerase holoenzymes. genetic code The linear sequences of nucleotides that specify the amino acids during the process of translation at the ribosome.
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genetic engineering Popular term for recombinant DNA technology. See recombinant DNA technology. genetic load The relative decrease in the mean tness of a population due to the presence of genotypes that have less than the highest tness. genetic polymorphism The occurrence together in the same population of more than one allele at the same locus, with the least frequent allele occurring more frequently than can be accounted for by mutation. genic balance theory Bridges s theory that the sex of a fruit y is determined by the relative number of X chromosomes and autosomal sets. genome The entire genetic complement of a prokaryote or virus or the haploid genetic complement of a eukaryote. genomic equivalence The concept that differentiated cells in a eukaryotic organism have identical genetic contents. genomic library A set of cloned fragments making up the entire genome of an organism or species. genomics The study of the mapping and sequencing of genomes. Bioinformatics is the science of mining the data from these DNA sequences obtained from sequencing. genophore The chromosome (genetic material) of prokaryotes and viruses. genotype The genes that an organism possesses. Giemsa stain A complex of stains speci c for the phosphate groups of DNA. Goldstein-Hogness box See TATA box. green uorescent protein A reporter system that uses the gene from a jelly sh that speci es a protein that uoresces green when ultraviolet light is shined on it, indicating the success of a transfection experiment. group I introns Self-splicing introns that require a guanine-containing nucleotide for splicing; the intron is released in a linear form. group II introns Self-splicing introns that do not require an external nucleotide for splicing; the intron is released in a lariat form. group selection Selection for traits that would be bene cial to a population at the expense of the individual possessing the trait. G-tetraplex A structure of four guanines that can base pair to form a planar structure that may be involved in novel structures at the end of eukaryotic chromosomes. guanine See purines. guide RNA (gRNA) RNA that guides the insertion of uridines (RNA editing) into messenger RNAs in trypanosomes. Found in transcripts from minicircles and maxicircles of DNA in kinetoplasts. gynandromorphs Mosaic individuals having simultaneous aspects of both the male and the female phenotype.
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