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1. Mendel crossed tall pea plants with dwarf ones. The F1 plants were all tall. When these F1 plants were selfed to produce the F2 generation, he got a 3:1 tallto-dwarf ratio in the offspring. Predict the genotypes and phenotypes and relative proportions of the F3 generation produced when the F2 generation was selfed. 2. What properties of fruit ies and corn made them the organisms of choice for geneticists during most of the rst half of the twentieth century (Molecular geneticists have made great strides working with bacteria and viruses.You could begin thinking at this point about the properties that have made these organisms so valuable to geneticists.) 3. State precisely the rules of segregation and independent assortment. (See also the Exercises and Problems section on Independent Assortment.) 4. In Drosophila, a cross between a dark-bodied y and a tan-bodied y yields seventy-six tan and eighty dark ies. Diagram the cross.
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5. If two black mice are crossed, ten black and three white mice result. a. Which allele is dominant b. Which allele is recessive c. What are the genotypes of the parents 6. In Drosophila, two red-eyed ies mate and yield 110 red-eyed and 35 brown-eyed offspring. Diagram the cross and determine which allele is dominant.
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7. Explain how Tay-Sachs disease can be both a recessive and an incomplete dominant trait. What are the differences between incomplete dominance and codominance 8. How does the biochemical pathway in gure 2.13 explain how alleles I A and I B are codominant, yet both dominant to allele i
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*Answers to selected exercises and problems are on page A-1.
Tamarin: Principles of Genetics, Seventh Edition
II. Mendelism and the Chromosomal Theory
2. Mendel s Principles
The McGraw Hill Companies, 2001
Two Mendel s Principles
9. Two short-eared pigs are mated. In the progeny, three have no ears, seven have short ears, and four have long ears. Explain these results by diagramming the cross. 10. A plant with red owers is crossed with a plant with white owers. All the progeny are pink. When the plants with pink owers are crossed, the progeny are eleven red, twenty-three pink, and twelve white. What is the mode of inheritance of ower color
NOMENCLATURE
11. In fruit ies, a new dominant trait, washed eye, was discovered. Describe different ways of naming the alleles of the washed-eye gene. 12. The following is a list of ten genes in fruit ies, each with one of its alleles given. Are the alleles shown dominant or recessive Are they mutant or wildtype What is the alternative allele for each Is the alternative allele dominant or recessive in each case
Name of Gene yellow Hairy wing Abruptex Con uens raven downy Minute(2)e Jammed tufted burgundy Allele y Hw Ax Co rv dow M(2)e J tuf bur
single gene. What types of constraints might exist to set a limit on the number of alleles a gene can have 17. In the human ABO blood system, the alleles I A and I B are dominant to i. What possible phenotypic ratios do you expect from a mating between a type A individual and a type B individual 18. In screech owls, crosses between red and silver individuals sometimes yield all red; sometimes 1/2 red:1/2 silver; and sometimes 1/2 red:1/4 white:1/4 silver offspring. Crosses between two red owls yield either all red, 3/4 red:1/4 silver, or 3/4 red:1/4 white offspring. What is the mode of inheritance 19. A premed student, Steve, plans to marry the daughter of the dean of nursing. The dean s husband was sterile, and the daughter was conceived by arti cial insemination. Steve s father puts pressure on Steve to marry someone else. Having served as an anonymous sperm donor, he is concerned that Steve and his anc may be half brother and sister. Given the following information, deduce whether Steve and his anc could be related. (The MN and Ss systems are two independent, codominant blood-type systems.)
Blood Type Dean Her daughter Steve s father Steve Steve s mother A, MN, Ss O, M, S A, MN, Ss O, N, s B, N, s
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